Determination of endocrine disrupting compounds in human placenta by UPLCESI-MS/MS

Conclusions of the presentation given at the 11th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-11)

• Sensitive analytical method was developed
• Endocrine disrupting chemicals (EDC) could be quantified in human placenta samples
• The major compounds found were parabens and bisphenols
• Highest concentration levels for methyl- and propylparaben and highest quantification frequency for octylphenol and ethylparaben
• Bisphenol A and bisphenol S both detected and quantified
• Enlarging the number of samples will enable to correlate EDC levels in placenta with health outcomes of the born children