DNA ploidy and nuclear morphometric variables for the evaluation of melanocytic tumors in dogs and cats.

Last updated on 22-8-2019 by Anonymous (not verified)

Peer reviewed scientific article

SCIENSANO

Abstract:

OBJECTIVE: To determine the prognostic importance of the DNA content and nuclear morphometric variables in melanocytic tumors of cats and dogs.SAMPLE POPULATION: 27 melanocytic tumors of dogs and cats.PROCEDURES: Biopsy specimens were investigated by quantitative image analysis after the Feulgen staining method. The DNA content (index), nuclear diameter, ploidy balance, proliferation index, hyperploidy, and growth fraction (Ki67) were measured. Using 1-way ANOVA and a Pearson correlation test, the relationships between the different variables were tested. Their role in the prognosis in affe…

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