Exploring HIV-1 Transmission Dynamics by Combining Phylogenetic Analysis and Infection Timing

Last updated on 14-1-2022 by Jessika Deblonde

Public Access


Peer reviewed scientific article



HIV-1 pol sequences obtained through baseline drug resistance testing of patients newly diagnosed between 2013 and 2017 were analyzed for genetic similarity. For 927 patients the information on genetic similarity was combined with demographic data and with information on the recency of infection. Overall, 48.3% of the patients were genetically linked with 11.4% belonging to a pair and 36.9% involved in a cluster of ≥3 members. The percentage of early diagnosed (≤4 months after infection) was 28.6%. Patients of Belgian origin were more frequently involved in transmission clusters (…

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