TY - JOUR T1 - Bordetella pertussis seroprevalence in Belgian adults aged 20-39 years, 201234005 JF - Epidemiol.Infect. Y1 - 2014 A1 - K Huygen A1 - C Rodeghiero A1 - Govaerts,D. A1 - G. Leroux-Roels A1 - Melin,P. A1 - Reynders,M. A1 - Van Der Meeren,S. A1 - Van Den Wijngaert,S. A1 - Denis PiƩrard KW - 2012 KW - a KW - acute KW - Adult KW - adults KW - age KW - AGE GROUP KW - Age-group KW - Aged KW - an KW - antibodies KW - Antibody KW - article KW - AS KW - Belgian KW - Belgian population KW - Belgium KW - Bordetella pertussis KW - Brussels KW - Bruxelles KW - chemistry KW - Clinical KW - comparing KW - Context KW - cutoff KW - electronic KW - European KW - Flanders KW - Group KW - Healthy KW - im KW - INFECTION KW - IS KW - journal KW - Laboratories KW - LEVEL KW - levels KW - ON KW - past KW - pertussis KW - POPULATION KW - region KW - report KW - Research KW - Research Support KW - result KW - results KW - Sample KW - Samples KW - SB - IM KW - SELECTED KW - serum KW - State KW - States KW - study KW - summary KW - Wallonia KW - WIV-ISP AB - SUMMARY The last report on pertussis seroprevalence in Belgium concerned samples collected during 1993-1994. In the context of the Eupert-Labnet WP6 seroprevalence study (comparing sera from 16 European member states), 1500 anonymized leftover diagnostic samples were collected randomly during the second semester of 2012 by the clinical chemistry laboratories of six participating Belgian centres, distributed equally between Flanders, Wallonia and Brussels Capital Region. As suggested by the WP6 organizers, a total of 750 samples (125/centre) were selected from subjects in the 20-29 years age group and 750 samples (125/centre) from subjects in the 30-39 years age group. Anti-PT IgG levels were measured using Virion-Serion ELISA and analysed using predefined cut-off levels. Sixty-one (4%) sera were indicative of an infection in the past 2 years (between 50 and 100 IU/ml) and another 61 (4%) sera had anti-PT IgG antibodies reflecting acute infection (>100 IU/ml). These results highlight the presence of a Bordetella pertussis reservoir in the adult 'healthy' Belgian population VL - 142 CP - 4 U1 - 39176 M3 - http://dx.doi.org/10.1017/S0950268813002458 ER -