TY - JOUR T1 - Comparative analysis of monoclonal antibodies against pestiviruses: report of an international workshop. JF - Vet Microbiol Y1 - 1989 A1 - Ann Brigitte Cay A1 - Chappuis, G A1 - Coulibaly, C A1 - Dinter, Z A1 - Edwards, S A1 - Greiser-Wilke, I A1 - Gunn, M A1 - Have, P A1 - Hess, G A1 - Juntti, N KW - Animals KW - Antibodies, Monoclonal KW - Antibodies, Viral KW - Cell Line KW - Cross Reactions KW - Fluorescent Antibody Technique KW - Immunoenzyme Techniques KW - mice KW - Pestivirus AB -

Thirty-three pestivirus strains were grown in cell culture and characterized by immunostaining with 19 monoclonal antibodies (MAbs) raised against hog cholera virus (HCV), with 42 MAbs against bovine viral diarrhoea virus (BVDV) and with 13 MAbs against border disease virus (BDV). Seven MAbs reacted with all pestivirus strains tested, eight MAbs detected only the seven HCV strains, three detected only the 16 BVDV strains. No MAb was found that was specific for BDV. BVDV and BDV strains were broadly cross-reactive with the MAbs, indicating a close relationship between these two species, whereas HCV strains were characterized as distinct from BVDV and BDV.

VL - 20 CP - 2 U1 - http://www.ncbi.nlm.nih.gov/pubmed/2549680?dopt=Abstract ER -