TY - JOUR T1 - Impact of rotavirus vaccination on laboratory confirmed cases in Belgium. JF - Vaccine Y1 - 2011 A1 - Hanquet, Germaine A1 - Ducoffre, Geneviève A1 - Vergison, Anne A1 - Neels, Pieter A1 - Martine Sabbe A1 - Van Damme, Pierre A1 - Van Herck, Koen KW - Belgium KW - Child, Preschool KW - Humans KW - Infant KW - Infant, Newborn KW - Rotavirus Infections KW - Rotavirus Vaccines KW - Vaccination AB -

Rotavirus vaccines were introduced in Belgium in 2006 and recommended in the universal schedule in January 2007. We measured the impact of rotavirus vaccination through an active laboratory-based surveillance system. In 2008, the number of laboratory confirmed rotavirus cases declined by 61.4% (95% CI 60.2-62.6%) compared to the 2005-2006 pre-vaccination period, with the highest decline in children<1 year (80.1%; 95% CI 78.7-81.4%). The rotavirus season was delayed compared to pre-vaccination seasons. Laboratory data provide a crude estimation of vaccination impact, but analysis of in-patient data will be needed to assess the impact on severe disease.

VL - 29 CP - 29-30 U1 - http://www.ncbi.nlm.nih.gov/pubmed/21571023?dopt=Abstract M3 - 10.1016/j.vaccine.2011.04.098 ER -