TY - JOUR T1 - Nontuberculous mycobacteria among pulmonary tuberculosis patients: a retrospective Belgian multicenter study. JF - Acta Clin Belg Y1 - 2017 A1 - De Keukeleire, Steven A1 - Vanessa Mathys A1 - Van den Wijngaert, Sigi A1 - Van De Vyvere, Martine A1 - Jonckheere, Stijn A1 - De Beenhouwer, Hans A1 - de Bel, Annelies A1 - Arrazola de Oñate, Wouter A1 - Wanlin, Maryse A1 - Piérard, Denis A1 - Nulens, Eric A1 - Saegeman, Veroniek KW - Adult KW - Belgium KW - Coinfection KW - Female KW - Humans KW - Male KW - middle aged KW - Mycobacterium Infections, Nontuberculous KW - Nontuberculous Mycobacteria KW - Retrospective Studies KW - Tuberculosis, Pulmonary AB -

OBJECTIVES: Currently, there are no European data about the frequency and clinical significance of nontuberculous mycobacteria (NTM) grown from respiratory samples during the treatment of tuberculosis (TB). We determined the frequency and clinical significance of NTM isolated before or during pulmonary tuberculosis treatment in Belgian laboratories.

METHODS: We conducted a nationwide retrospective multicenter cohort study on the co-isolation of TB and NTM in Belgium. Starting from laboratory data between 2006 and 2013, possible TB-NTM co-isolations were searched for.

RESULTS: A total of 2569 unique culture-positive pulmonary tuberculosis cases were included in the study. Only 35 (1.4%) of these TB cases had an NTM co-isolated, and two of these 35 fulfilled the ATS criteria for NTM lung disease.

CONCLUSION: A very low prevalence of 1.4% NTM co-isolations was found in Belgian patients with culture-proven pulmonary TB.

VL - 72 CP - 1 U1 - http://www.ncbi.nlm.nih.gov/pubmed/27345031?dopt=Abstract M3 - 10.1080/17843286.2016.1200823 ER -