TY - JOUR T1 - Detection of Plasmid-Mediated Colistin Resistance, mcr-1 and mcr-2 Genes, in Salmonella spp. Isolated from Food at Retail in Belgium from 2012 to 2015. JF - Foodborne Pathog Dis Y1 - 2017 A1 - Cristina Garcia-Graells A1 - Sigrid C.J. De Keersmaecker A1 - Nguyen, Quang Trung A1 - Anthonissen,R.. A1 - Raf Aerts A1 - Nancy Roosens A1 - Katelijne Dierick A1 - N Botteldoorn KW - colistin resistance AB -

A collection of 105 colistin-resistant Salmonella isolates collected from 2012 to 2015 in the national surveillance program in Belgium was screened by PCR for the presence of genes mcr-1 and mcr-2. Of these, 1.90% (2/105) and 0.95% (1/105) tested positive for mcr-1 and mcr-2, respectively. The presence of the mcr-1 or mcr-2 determinant has been confirmed by whole genome sequencing and allowed the localization of these two genes on IncX4 type plasmids. We report here the presence of mcr-1 and the first mcr-2 gene in Salmonella ever isolated in the Belgian food chain. Although present at retail since 2012, the occurrence is low and sporadic.

M3 - 10.1089/fpd.2017.2329 ER -