%0 Journal Article %J Transbound Emerg Dis %D 2017 %T Nosocomial Intravascular Catheter Infections with Extended-spectrum Beta-lactamase-producing Escherichia coli in Calves after Strain Introduction from a Commercial Herd. %A Pardon, B %A Smet, A %A Butaye, P %A Argudín, M A %A Valgaeren, B %A Boudewijn Catry %A Haesebrouck, F %A Deprez, P %K Animals %K Bacterial Proteins %K beta-Lactamases %K Catheters %K Cattle %K Cattle Diseases %K Cross Infection %K Electrophoresis, Gel, Pulsed-Field %K Escherichia coli %K Escherichia coli Infections %K Hospitals, Animal %K Hospitals, Teaching %X

An outbreak of intravascular catheter-related infections by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in calves in an animal teaching hospital is reported. Pulsed-field gel electrophoresis was used for strain typing to determine the origin and dissemination of these strains. All 19 strains harboured the blaCTX-M-14, and six strains also overexpressed their chromosomal AmpC gene. Evidence on the introduction of the strain from a beef herd, experiencing neonatal diarrhoea and increased mortality, to the clinic through admission of diarrhoeic calves was provided. Strains isolated from phlebitis cases from other herds up to 5 months later showed a high similarity with the initial strain, suggesting that the strain had become nosocomial. The catheter infections with ESBL/AmpC-producing E. coli resulted in a prolonged hospitalization, increased anti-microbial use and mortality. This report points towards the potential dangers of the emergence of ESBL/AmpC-producing bacteria in susceptible food animals and warns farmers and veterinarians for the facility by which they are introduced into another environment.

%B Transbound Emerg Dis %V 64 %P 130-136 %8 2017 Feb %G eng %N 1 %1 http://www.ncbi.nlm.nih.gov/pubmed/25903854?dopt=Abstract %R 10.1111/tbed.12352