<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Luko C Masungi</style></author><author><style face="normal" font="default" size="100%">Vansanten, G</style></author><author><style face="normal" font="default" size="100%">Ryelandt, M</style></author><author><style face="normal" font="default" size="100%">Denis, O</style></author><author><style face="normal" font="default" size="100%">Wuilmart, C</style></author><author><style face="normal" font="default" size="100%">Andris, F</style></author><author><style face="normal" font="default" size="100%">Van Acker, A</style></author><author><style face="normal" font="default" size="100%">Brait, M</style></author><author><style face="normal" font="default" size="100%">Cloquet, J P</style></author><author><style face="normal" font="default" size="100%">Ismaili, N</style></author><author><style face="normal" font="default" size="100%">Nisol, F</style></author><author><style face="normal" font="default" size="100%">Latinne, D</style></author><author><style face="normal" font="default" size="100%">Brown, A</style></author><author><style face="normal" font="default" size="100%">Leo, O</style></author><author><style face="normal" font="default" size="100%">Bazin, H</style></author><author><style face="normal" font="default" size="100%">Urbain, J</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Distinct VH repertoires in primary and secondary B cell lymphocyte subsets in the preimmune repertoire of A/J mice: the CRI-A idiotype is preferentially associated with the HSA(low) B cell subset.</style></title><secondary-title><style face="normal" font="default" size="100%">Eur J Immunol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Eur J Immunol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Antigens</style></keyword><keyword><style  face="normal" font="default" size="100%">B-Lymphocyte Subsets</style></keyword><keyword><style  face="normal" font="default" size="100%">Base Sequence</style></keyword><keyword><style  face="normal" font="default" size="100%">Gene Rearrangement</style></keyword><keyword><style  face="normal" font="default" size="100%">Hemocyanins</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin D</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin Heavy Chains</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin Idiotypes</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin M</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin Variable Region</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunologic Memory</style></keyword><keyword><style  face="normal" font="default" size="100%">mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice, Inbred BALB C</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular Sequence Data</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2000</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2000 Aug</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">2322</style></number><volume><style face="normal" font="default" size="100%">30</style></volume><pages><style face="normal" font="default" size="100%">2312-22</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The anti-arsonate immune response of A/J mice is characterized by the occurrence of several recurrent idiotypes with a different temporal pattern of expression. The CRI-A idiotype is typically a memory idiotype since it appears late in the primary and dominates the secondary as well as subsequent immune responses. The CRI-C idiotype is present throughout the responses, including the primary one. Naive adult A/J mice treated repeatedly with anti-mu or anti-delta monoclonal antibodies exhibit a completely different balance of HSA(low) and HSA(high) B cell subsets and an opposite idiotype profile after immunization with p-azophenylarsonate coupled to hemocyanin. Anti-mu treatment leads to a striking enhancement of the HSA(low) cell subset associated with an earlier important synthesis of CRI-A(+) antibodies, while anti-delta treatment enhances significantly the HSA(high) compartment with a strong decrease of CRI-A and persistence of CRI-C1 antibodies. Semiquantitative PCR analysis reveals that the presence of CRI-A transcripts is associated with the HSA(low) compartment, while CRI-C transcripts are mainly associated with HSA(high) B cell subsets. This has been demonstrated with spleen cells of adult A/J mice treated with anti-mu or anti-delta antibodies and also with purified B cell subsets of unimmunized adult A/J mice and on neonatal spleen cells. It appears that the memory (CRI-A) idiotype is selected into the HSA(low) B cell subset before antigen arrival.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">8</style></issue><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/10940922?dopt=Abstract</style></custom1><section><style face="normal" font="default" size="100%">2312</style></section></record></records></xml>