<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Guy Berbers</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Pieter Van Gageldonk</style></author><author><style face="normal" font="default" size="100%">Jan van de Kassteele</style></author></secondary-authors><tertiary-authors><author><style face="normal" font="default" size="100%">Ursula Wiedermann</style></author></tertiary-authors><subsidiary-authors><author><style face="normal" font="default" size="100%">I Desombere</style></author><author><style face="normal" font="default" size="100%">Tine Dalby</style></author><author><style face="normal" font="default" size="100%">Julie Toubiana</style></author><author><style face="normal" font="default" size="100%">Tsiodras, Sotirios</style></author><author><style face="normal" font="default" size="100%">Ildikó Paluska Ferencz</style></author><author><style face="normal" font="default" size="100%">Kathryn Mullan</style></author><author><style face="normal" font="default" size="100%">Algirdas Griskevicius</style></author><author><style face="normal" font="default" size="100%">Tatjana Kolupajeva</style></author><author><style face="normal" font="default" size="100%">Vestrheim, Didrik Frimann</style></author><author><style face="normal" font="default" size="100%">Paula Palminha</style></author><author><style face="normal" font="default" size="100%">Odette Popovici</style></author><author><style face="normal" font="default" size="100%">Lena Wehlin</style></author><author><style face="normal" font="default" size="100%">Tamara Kastrin</style></author><author><style face="normal" font="default" size="100%">Lucia Maďarová</style></author><author><style face="normal" font="default" size="100%">Helen Campbell</style></author><author><style face="normal" font="default" size="100%">Csaba Ködmön</style></author><author><style face="normal" font="default" size="100%">Sabrina Bacci</style></author><author><style face="normal" font="default" size="100%">Alex-Mikael Barkoff</style></author><author><style face="normal" font="default" size="100%">He, Qiushui</style></author></subsidiary-authors><translated-authors><author><style face="normal" font="default" size="100%">Serosurveillance Study Team</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries.</style></title><secondary-title><style face="normal" font="default" size="100%">Nat Commun</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Antibodies, Bacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Bordetella pertussis</style></keyword><keyword><style  face="normal" font="default" size="100%">Diphtheria</style></keyword><keyword><style  face="normal" font="default" size="100%">Diphtheria-Tetanus-Pertussis Vaccine</style></keyword><keyword><style  face="normal" font="default" size="100%">Europe</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunoglobulin G</style></keyword><keyword><style  face="normal" font="default" size="100%">middle aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Seroepidemiologic Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Tetanus</style></keyword><keyword><style  face="normal" font="default" size="100%">Whooping Cough</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 May 17</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Reported incidence of pertussis in the European Union (EU) and the European Economic Area (EEA) varies and may not reflect the real situation, while vaccine-induced protection against diphtheria and tetanus seems sufficient. We aimed to determine the seroprevalence of DTP antibodies in EU/EEA countries within the age groups of 40-49 and 50-59 years. Eighteen countries collected around 500 samples between 2015 and 2018 (N = 10,302) which were analysed for IgG-DTP specific antibodies. The proportion of sera with pertussis toxin antibody levels ≥100 IU/mL, indicative of recent exposure to pertussis was comparable for 13/18 countries, ranging between 2.7-5.8%. For diphtheria the proportion of sera lacking the protective level (&amp;lt;0.1 IU/mL) varied between 22.8-82.0%. For tetanus the protection was sufficient. Here, we report that the seroprevalence of pertussis in these age groups indicates circulation of B. pertussis across EU/EEA while the lack of vaccine-induced seroprotection against diphtheria is of concern and deserves further attention.&lt;/p&gt;
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