<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Salvatore Ciano</style></author><author><style face="normal" font="default" size="100%">Mélanie Di Mario</style></author><author><style face="normal" font="default" size="100%">Séverine Goscinny</style></author><author><style face="normal" font="default" size="100%">Matthieu Legros</style></author><author><style face="normal" font="default" size="100%">Els Van Hoeck</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Combined untargeted screenings of substances migrating from emerging food contact materials</style></title><secondary-title><style face="normal" font="default" size="100%">41st International Conference on Environmental &amp; Food Monitoring (ISEAC)</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">food contact materials</style></keyword><keyword><style  face="normal" font="default" size="100%">iAs</style></keyword><keyword><style  face="normal" font="default" size="100%">Migration</style></keyword><keyword><style  face="normal" font="default" size="100%">NIAS</style></keyword><keyword><style  face="normal" font="default" size="100%">untargeted screening</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year></dates><pub-location><style face="normal" font="default" size="100%">Amsterdam</style></pub-location><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The growing recognition among the general public regarding the environmental issues associated with fossil-based plastics, coupled with the rising demand for sustainability, has triggered the development of alternatives in the Food Contact Materials (FCM) sector. Bio-based and/or bio-degradable polymers, fibrous material (e.g. bagasse) and wood analogues (bamboo, palm leaf, coconut, reed) are examples of substitute materials, and they must comply with Regulation (EC) No 1935/2004. However, specific harmonized legislation is only available for plastic FCM, and the understanding of migrating chemicals remains unknown or unidentified. The study aims to bridge this gap, outlining a typical workflow that can be applied to identifying unknown compounds in emerging FCM so that a better overview of (non)-intentionally added substances can be used for safety and exposure assessments.&lt;/p&gt;

&lt;p&gt;In the study, 99 substitute FCM were selected. Next, migration experiments were performed according to the Kitchenware guidelines&lt;sup&gt;1&lt;/sup&gt; of the European Reference Laboratory (EURL), using simulants B (3% acetic acid) and D2 (95% ethanol) as worst-case. Afterwards, the solutions were analysed by full scan Gas Chromatography – Mass Spectrometry (GC-MS) and Liquid Chromatography – High-Resolution Mass Spectrometry (LC-HRMS). The tentative identification was performed using a workflow including spectral deconvolution followed by spectral matching with commercial mass spectral libraries. A data reduction strategy based on procedural blank subtraction was also applied to improve further data analysis.&lt;/p&gt;

&lt;p&gt;Finally, the applicability of the developed combined approach for assessing (non)-intentionally added substances in substitute FCMs was demonstrated.&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Acknowledgement&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;The research that yielded these results was funded by the Belgian Federal Public Service of Health, Food Chain Safety and Environment through the contract TREFCOM (RT 21/4).&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;References&lt;/strong&gt;:&lt;/p&gt;

&lt;p&gt;(1)&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp; Beldi, G.; Senaldi, C.; Robouch, P.; Hoekstra, E. Testing Conditions for Kitchenware Articles in Contact with Foodstuffs: Plastics, Metals, Silicone &amp;amp; Rubber. &lt;strong&gt;2021&lt;/strong&gt;.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">International Association of Environmental Analytical Chemistry</style></issue></record></records></xml>