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Lipoteichoic acid from Staphylococcus aureus exacerbates respiratory disease in porcine respiratory coronavirus-infected pigs34019

Last updated on 23-8-2019 by Anonymous (not verified)

Public Access

Published

Peer reviewed scientific article

DOI : http://dx.doi.org/10.1016/j.tvjl.2010.03.001

Authors

Atanasova,K.; Steven Van Gucht; Barbe,F.; Luc Duchateau; Van Reeth,K.

Keywords

  1. 0
  2. acid
  3. Acids
  4. Animal
  5. Animals
  6. article
  7. AS
  8. Belgium
  9. biosynthesis
  10. Bronchoalveolar Lavage Fluid
  11. Cell
  12. cells
  13. Clinical
  14. Coronavirus
  15. Coronavirus Infections
  16. Cytokines
  17. disease
  18. drug effects
  19. electronic
  20. Female
  21. im
  22. immunology
  23. IS
  24. journal
  25. Lipopolysaccharides
  26. Lung
  27. Male
  28. metabolism
  29. Objective
  30. pathology
  31. pharmacology
  32. Pig
  33. Pigs
  34. Porcine Respiratory Coronavirus
  35. Random Allocation
  36. Research
  37. Research Support
  38. Respiratory
  39. Respiratory disease
  40. Respiratory Tract Diseases
  41. S
  42. SB - IM
  43. Severity of Illness Index
  44. staphylococcus
  45. Staphylococcus aureus
  46. study
  47. Swine
  48. Swine Diseases
  49. Teichoic Acids
  50. Universities
  51. university
  52. veterinary
  53. virology
  54. VIRUS

Abstract:

The objective of this study was to assess if lipoteichoic acid (LTA), produced by Staphylococcus aureus, exacerbates respiratory disease in porcine respiratory coronavirus (PRCV)-infected pigs, as has previously been shown with lipopolysaccharide. Piglets were inoculated with PRCV and 24h later with S. aureus LTA. Clinical signs, lung virus titres, inflammatory cells and cytokines in bronchoalveolar lavage fluid (BALF) were compared with those of animals in
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