Multiple HPV infections with high viral loads are associated with cervical lesions but do not differentiate grades of cervical abnormalities

Last updated on 23-8-2019 by Anonymous (not verified)

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Peer reviewed scientific article

Abstract:

Multiple human papillomavirus (HPV) genotypes often co-exist within the cervical epithelium and are frequently detected in smears of different grades of cervical neoplasia. Describing the association of multiple infections with cervical disease is important to generate hypotheses regarding its pathogenesis.We analyzed the prevalence of multiple HPV infections and their attribution to cervical disease in a screening population of 999 consecutive BD-SurePath liquid-based cervical cytology samples enriched with additional ASC-US (n=100), LSIL (n=100) and HSIL (n=97). HPV genotyping was perform…

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