Last updated on 3-5-2022 by Katelijne Dierick
Public Access
Peer reviewed scientific article
English
SCIENSANO
Authors
Pieter Pannus; Kristof Y Neven; Stéphane De Craeye; Heyndrickx, Leo; Sara Vande Kerckhove; Daphnée Georges; Johan Michiels; Antoine Francotte; Marc Van den Bulcke; Maan Zrein; Steven Van Gucht; Marie-Noëlle Schmickler; Mathieu Verbrugghe; André Matagne; Isabelle Thomas; Katelijne Dierick; Joshua A Weiner; Margaret E Ackerman; Stanislas Goriely; Maria Goossens; Ariën, Kevin K; I Desombere; Arnaud MarchantKeywords
Abstract:
BACKGROUND: Residents of nursing homes (NH) are at high risk of COVID-19 related morbidity and death and may respond poorly to vaccination because of old age and frequent comorbidities.
METHODS: Seventy-eight residents and 106 staff members, naïve or previously infected with SARS-CoV-2, were recruited in NH in Belgium before immunization with two doses of 30µg BNT162b2 mRNA vaccine at day 0 and day 21. Binding antibodies (Ab) to SARS-CoV-2 receptor binding domain (RBD), spike domains S1 and S2, RBD Ab avidity, and neutralizing Ab against SARS-CoV-2 wild type and B.1.351 were assessed at …