RNA sequencing-based transcriptional overview of xerotolerance in Cronobacter sakazakii SP291.

Last updated on 23-4-2020 by Koenraad Van Hoorde

Peer reviewed scientific article




Cronobacter sakazakii is a xerotolerant neonatal pathogen epidemiologically linked to powdered infant food formula, often resulting in high mortality rates. Here, we used transcriptome sequencing (RNA-seq) to provide transcriptional insights into the survival of C. sakazakii in desiccated conditions. Our RNA-seq data show that about 22% of the total C. sakazakii genes were significantly upregulated and 9% were downregulated during desiccation survival. When reverse transcription-quantitative PCR (qRT-PCR) was used to validate the R…

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