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M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
Publication Type: Peer reviewed scientific article Authors: Hedhli, Dorsaf; Olivier J Denis; Barkan, Daniel; Daffé, Mamadou; Glickman, Michael S; Huygen, Kris Source: PLoS One, Volume 8, Issue 10, ...
Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice
Publication Type: Peer reviewed scientific article Authors: Barkan,D.; Hedhli,D.; Yan,H-G.; K Huygen; Glickman,M.S. Source: Infect.Immun., Volume 80, Issue 6, Number 1968, p.1958- 1968 (2012) ...