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Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

protease that mediates the activation of several innate and adaptive immune cells in response to multiple receptors, and therapeutic MALT1 targeting is believed to be a valid approach for autoimmunity and ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

with autoimmunity and cancer, implicating MALT1 as a new therapeutic target. While MALT1 deficiency has been shown to protect against experimental autoimmune encephalomyelitis, nothing is known about the ...

Circulating Follicular Regulatory T Cells Are Defective in Multiple Sclerosis

Hellings,N. Source: J.Immunol., Volume 195, Issue 3, Number 840, p.832- 840 (2015) Keywords: alternative an article Autoimmune Diseases Belgium blood Brussels Cell cells Context Control de disease Diseases ...

From ANA-screening to antigen-specificity: an EASI-survey on the daily practice in European countries703

AS Autoantibodies Autoimmune Diseases Autoimmunity Awareness Biological Markers blood Countries detection Diagnosis Diagnostics differences disease Diseases Europe European European countries Health ...

Belgian recommendations on ANA, anti-dsDNA and anti-ENA antibody testing704

assessment Autoantibodies Autoimmune Diseases Autoimmunity Belgian Belgium blood Cell Line Clinical disease Diseases Dna European external External quality assessment External quality assessment scheme ...

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

Bénédicte Lambrecht; Bellier, Bertrand; Piaggio, Eliane; Bosch, Fatima; Klatzmann, David Source: Clin Immunol, Volume 151, Issue 2, p.114-26 (2014) Keywords: Animals Autoimmunity Female Gene Expression ...

Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.

As treatment of auto-immune diseases with anti- IL-17A antibodies is actually being tested in clinical studies, our data suggest that caution should be taken with respect to possible reactivation ...

High prevalence of thyroid disorders in pregnant women in a mildly iodine-deficient country: a population-based study

Issue 9, Number 3701, p.3694- 3701 (2013) Keywords: an antibodies Antibody association Autoimmunity Belgium clinic Clinics Context Countries Creatinine data Deficiency Design disease Disorder Disorders ...

Anti-TNF-alpha therapy does not ameliorate disease in a model of acute virus-endotoxin mediated respiratory disease in pigs36852

Keywords: 0 a Activity acute Acute Disease ALL analysis Animal Animals antagonists & inhibitors article AS at Autoimmune Diseases Belgium Bronchoalveolar Lavage Fluid Cell Clinical conditions Control ...

Performance of automated measurement of antibodies to cyclic citrullinated peptide in the routine clinical laboratory

Clinical verification of both methods included estimation of sensitivity in RA patients (n = 42) and specificity in well-characterized non- RA autoimmune disease controls (n = 49) and healthy subjects (n ...

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