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Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

Ampe; Vangoitsenhoven, Roman; Ann Mertens; Rudi Vennekens; Van der Schueren, Bart Source: European Journal of Drug Metabolism and Pharmacokinetics, Volume 47, Issue 6 (2022) Abstract: Background ...

Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study.

were infrequent. Genetic analysis did not support parasitological resistance to ACT, suggesting prospective pharmacokinetic studies should assess adequacy of partner drug dosage and duration of treatment ...

In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract

aglycones (11.82%) and glycosides (16.17%). ADME, pharmacokinetic and drug-likeness assessment of major flavonoids of ELBE, using the web tool SwissADME, showed good oral bioavailability. The protective ...

Global burden of late-stage chronic kidney disease resulting from dietary exposure to cadmium, 2015

reported pharmacokinetic model describing the relationship between dietary cadmium intake and urinary cadmium (UC d), as well as a previously published dose-response relationship between UC d and GFR. ...

Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991

genetics identification im Institute IS IT journal Laboratories mechanism metabolism Mutation Mycobacterium Mycobacterium tuberculosis Pa PAS pharmacokinetics pharmacology prevent Prodrugs protein Proteins ...

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors31058

Models,Molecular Mycobacterium Mycobacterium tuberculosis ON Oxadiazoles pathogen Pharmacokinetic pharmacokinetics Piperidines PROCESSES Prodrugs protein Proteins Repressor Proteins Research Research Support SB- IM ...

A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation86

electronic estimation Genetic Immunosuppressive Agents intake IS journal LEVEL levels means MODEL modeling Objective ON parameters Patient patients period Pharmacokinetic pharmacokinetics POPULATION present ...

Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection36574

interactions IS journal Kinetics Lung lymphocyte Lymphocytes Macrophage Macrophages MODEL models Mycobacterium Mycobacterium tuberculosis need observed ON pathology Pharmacokinetic prevention & control rats ...

Pharmacokinetics of a loading dose of amikacin in septic patients undergoing continuous renal replacement therapy87

Patient patients Pharmacokinetic pharmacokinetics plasma Pseudomonas Pseudomonas aeruginosa RANGE RENAL Renal Replacement Therapy Replacement therapy result Sample Samples SB- IM serum Shock,Septic study ...

Population pharmacokinetic modeling and optimal sampling strategy for Bayesian estimation of amikacin exposure in critically ill septic patients88

Female Humans im IS journal Less Male meeting Metabolic Clearance Rate methods middle aged MODEL modeling Models,Biological need ON parameters Patient patients performance Pharmacokinetic pharmacokinetics ...

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