Search results - 8 results
Design, synthesis and pharmacological characterization of endomorphin analogues with non-cyclic amino acid residues in position 24386
pharmacology physiopathology profile Profiles Protein Binding RATES rats Receptor receptors Receptors,Opioid,delta Receptors,Opioid,mu Research Research Support Residue SB- IM SELECTED series study Test ...
Identification of endomorphin-1 and endomorphin-2 binding sites in human mu-opioid receptor by antisense oligonucleotide strategy4389
Measurements medical metabolism mRNA observed Oligonucleotides Oligonucleotides,Antisense Oligopeptides pain protein Receptor receptors Receptors,Opioid,mu Research Research Support response Responses Reverse ...
Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 24391
chemistry Comparison electronic Functional im Inhibitory Concentration 50 Institute IS journal Laboratories medical Oligopeptides Piperidines Proline rats Receptor receptors Receptors,Opioid,mu Research ...
Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure4392
metabolism mice Oligopeptides ON Pain Measurement pharmacology profile Protein Conformation Receptor receptors Receptors,Opioid,mu report Research Research Support SB- IM Spectrometry,Mass,Fast Atom ...
Mu-opioid receptor ligands lack receptor subtype selectivity in the aequorin luminescence-based calcium assay4393
Functional Human im in vivo Institute IS journal Laboratories LEVEL levels Ligands Luminescent Measurements medical metabolism ON POPULATION present Print Receptor receptors Receptors,Opioid,mu Research ...
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2)4395
Oligopeptides ON pharmacology physiology Print rats Receptor receptors Receptors,Opioid,delta Receptors,Opioid,mu Research Research Support Residue SB- IM series Structure-Activity Relationship Test Universities ...
[D-1-Nal4]endomorphin-2 is a potent micro-opioid receptor antagonist in the aequorin luminescence-based calcium assay4398
receptors Receptors,Opioid recombinant relative Research Research Support result results SB- IM series structure study Test Universities university Abstract: A functional assay, based on aequorin-derived ...
Functional characterization of opioid receptor ligands by aequorin luminescence-based calcium assay4399
a similar rank order of potency for the mu- and delta-opioid receptor agonists in both functional assays. The highest potency at the mu-receptor was observed for endomorphin-1, endomorphin-2, and ...