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Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.
assessment (ERA). An important element to be assessed as part of the ERA is the incidence of exposure to OV of individuals, other than the trial subjects, and the environment. The evidence-based evaluation of ...
Intra- and interlaboratory reproducibility of the RIATOL qPCR HPV genotyping assay.
Results Uterine Cervical Neoplasms Abstract: The implementation of cervical screening based on human papillomavirus (HPV) continues to progress rapidly across countries. Evidence has shown that assays ...
Whole-Genome Sequencing-Based Antimicrobial Resistance Characterization and Phylogenomic Investigation of 19 Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Positive Escherichia coli Strains Collected From Hospital Patients in Benin in 2019.
typing and single-nucleotide polymorphism-based phylogenomic methods were used to investigate the relatedness between samples. The broader phylogenetic context was characterized through the inclusion of ...
Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
cell-based neutralisation assay to support prior in vivo potency data that was available for some, but not all, of the antibodies. In addition, antibody affinity was measured, and epitope competition analysis ...
Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
a cell-based toxin neutralisation test and diphtheria toxin-domain recognition was determined by Western blotting. In addition, antibody affinity was measured, and epitope competition analysis was performed to ...
Diagnostic testing in myeloid malignancies by next-generation sequencing: recommendations from the commission personalised medicine
Commission of Personalised Medicine was founded to give professional and evidence-based advice on the molecular analysis in haemato-oncology. This paper describes its recommendations for NGS analysis in ...
Utilization of gabapentin by people in treatment for substance use disorders in Belgium (2011-2014): a cross-sectional study.
descriptive study with matching. Two datasets were used and linked at individual level. Subjects were selected based on their first registration in the database of the Treatment Demand Indicator (TDI) between ...
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
“margin of safety” (MoS) is calculated. This uncertainty factor is based on the systemic no observable (adverse) effect level (NO (A) EL) which can be derived from in vivo repeated dose toxicity studies. As ...
The German and Belgian accreditation models for diabetic foot services.
32 Suppl 1, p.318-25 (2016) Keywords: Accreditation Belgium Combined Modality Therapy Congresses as Topic Diabetic Foot Evidence-Based Medicine Germany Guideline Adherence HEALTH POLICY Humans Models, ...
Evidence for clinical applications of HR HPV testing.
NA (2013) Keywords: application applications at cancer cervix Clinical conference evidence Evidence-Based Medicine follow-up after treatment HPV meta-analysis primary screening Research triage Health ...