Search results - 55 results

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.

in silico modeling predicts further Alternaria toxins as potential estrogenic factors. Recent studies indicate also an immunosuppressive role of AOH and ATX- II; however, no data are available for the ...

Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples

RT-ddPCR method that targets the T19I amino acid mutation in the spike protein of the SARS-CoV-2 genomes, which is specific to the BA.2 variant (omicron). The T19I assay was evaluated both in silico and in ...

Design and Application of a Semi-automated Workflow including In Silico Models to support the Risk Assessment of Food Contact Material Substances

Publication Type: Scientific poster, presentation or proceeding Authors: Camille Streel; Ilse Van Overmeire; Gianluca Selvestrel; Alessandra Roncaglioni; Emilio Benfenati; Alessio Sommovigo; Alberto Manganaro; Els Van Hoeck; Birgit Mertens Source: BelTox ...

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying blaSCO-1 and blaDHA-1 Combined with Permeability Defects

ertapenem, third-generation cephalosporins and fluoroquinolones. A hybrid approach, combining long- and short-read sequencing, was employed for in silico plasmid characterization, multi-locus sequence typing ...

In Silico Methods for Chromosome Damage.

without the need for test material, several in silico tools for chromosome damage have been developed over the last years. In this chapter, a battery of freely available in silico chromosome damage ...

In silico methods for chromosome damage

Publication Type: Scientific book or chapter Authors: D. Baderna; Ilse Van Overmeire; G.J. Lavado; D. Gadaleta; Birgit Mertens Source: In silico methods for chromosome damage, Humana, Volume 2425, ...

Flanders and Brussels join forces to tackle animal testing

methods from various research fields and research fields and institutions. This includes using human material in cell and tissue cultures (in vitro), or computer models (in silico). “These new, innovative ...

Het RE-Place project focust op het bevorderen van alternatieve methoden die dierproeven kunnen helpen vervangen

proefdiervrije methoden. Onderzoekers maken onder andere gebruik van menselijk materiaal in cel- en weefselculturen (in vitro), of van computermodellen (in silico). Deze nieuwe, innovatieve technieken spelen een ...

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

of mutations present at low abundances using the mutations defining the SARS-CoV-2 lineage B.1.1.7 (alpha variant) as a case study. Real sequencing data were in silico modified by introducing mutations ...

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