Search results - 84 results

The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review

CONCLUSIONS: Drug resistance poses a serious threat to existing malaria therapies and chemoprevention options in the DRC. This review provides a baseline for monitoring public health efforts as well as evidence ...

Characterization of a Bacteriophage GEC_vB_Bfr_UZM3 Active against.

drug-resistant human pathogens, but cases of the refractory infections, caused by strains that are not susceptible to the common antibiotic regimes established for have been more frequently reported. ...

Optimization of Long-Acting Bronchodilator Dose Ratios Using Isolated Guinea Pig Tracheal Rings for Synergistic Combination Therapy in Asthma and COPD.

tiotropium bromide monohydrate (TIO) to assess their synergistic potential. This was done using an appropriate ex vivo model of isolated perfused guinea pig tracheal rings, and pharmacological models of drug ...

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

Ampe; Vangoitsenhoven, Roman; Ann Mertens; Rudi Vennekens; Van der Schueren, Bart Source: European Journal of Drug Metabolism and Pharmacokinetics, Volume 47, Issue 6 (2022) Abstract: Background ...

The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).

Republic of the Congo Drug Resistance Female Humans Malaria, Falciparum Male middle aged Mutation Plasmodium falciparum Polymorphism, Genetic Young adult Abstract: Artemisinin-based combination therapies ...

Incidence rate, predictors and outcomes of interruption of HIV care: nationwide results from the Belgian HIV cohort

and were therefore considered as having experienced a real gap in HIV care; they represented 2.3/100 person-years of follow-up. Factors individually associated with HCI were no antiretroviral therapy ...

Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study.

residents. Here, we describe recent trends of imported malaria to Belgium and characterize the first cases of P.falciparum failure to artemisinin-based combination therapy (ACT). METHODS: National surveillance ...

Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

identified across nine genes, and individual phenotypes were predicted unless mutations of unknown association were also present. To identify how whole-genome sequencing might direct first-line drug therapy ...

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.

Françoise Benoit-Vical; Pierrette Melin; Patrick De Mol; Marie-Pierre Hayette Source: PLoS One, Volume 12, Issue 6 (2017) Keywords: Artemisinins Democratic Republic of the Congo Drug Resistance Drug Therapy ...

Public health risk of antimicrobial resistance transfer from companion animals.

Volume 72, Issue 4, p.957-968 (2017) Keywords: Animals bacteria Bacterial Infections Disease Transmission, Infectious Drug Resistance, Bacterial Humans Pets Risk Assessment Zoonoses Abstract: ...

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