Search results - 18 results

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

and Th17 responses in mice in an OVA immunisation model, and that further analysis of their potential as novel adjuvants for subunit vaccines is warranted. Health Topics:  Health and disease monitoring ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

socioeconomic conditions, the increased incidence of drug-resistant M.tuberculosis strains and the co-infection with HIV (a major risk factor for development of TB). Currently only one vaccine is available against TB, the ...

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

Viral Base Sequence Bluetongue Bluetongue virus Capsid Proteins Cattle Cell Line Drug Stability Drug Storage Female Male Reverse Genetics Serogroup Sheep Vaccination Vaccines, Attenuated Vaccines, Subunit ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

Transduction Tuberculosis Vaccines Vaccines, Subunit Abstract: INTRODUCTION: Pathogen recognition receptors (PRR s) recognize pathogen-associated molecular patterns, triggering the induction of inflammatory ...

Novel GMO-Based Vaccines against Tuberculosis: State of the Art and Biosafety Considerations.

preclinical development. They fall into two categories, the one of candidates designed as a replacement of the Bacille Calmette Guérin (BCG) to be administered to infants and the one of sub-unit vaccines ...

Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.

Outbreaks Europe Female Reassortant Viruses RNA, Viral Serotyping Sheep, Domestic Vaccines, Subunit Viral Vaccines Virus Replication Abstract: Since 1998, 9 of the 26 serotypes of bluetongue virus (BTV) have ...

An update on vaccines for tuberculosis- there is more to it than just waning of BCG efficacy with time.

update on the ongoing Phase I and Phase II clinical trials is given. Finally, some of the most promising novel pre-clinical developments using live attenuated vaccines, sub-unit vaccines, prime-boost ...

Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines.

bovis Mycobacterium tuberculosis Th1 Cells Tuberculosis Tuberculosis Vaccines Vaccines, DNA Abstract: Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together ...

Identification of a dominant epitope in the hemagglutinin of an Asian highly pathogenic avian influenza H5N1 clade 1 virus by selection of escape mutants.

humans. The hemagglutinin (HA) is a glycoprotein on the surface of the virus envelope. Understanding its antigenic structure is essential for designing novel vaccines that can inhibit virus infection. The ...

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