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Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo
composed of small or large agglomerates with similar dispersion medium composition. For in vitro testing, human bronchial epithelial (HBE), colon epithelial (Caco2) and monocytic (THP-1) cell lines were ...
Is aggregated synthetic amorphous silica toxicologically relevant?
size distributions. Their effect on cell metabolic activity, cell viability, epithelial barrier integrity, total glutathione content and, IL-8 and IL-6 secretion were investigated after 24 h exposure in ...
Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice
epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses were 6, 18 ...
Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015.
vaccines and risk-based analysis resulting from insufficient data on the circulating FMD virus (FMDV) serotypes/strains. In 2013-2015, blood and epithelial samples were collected from reported FMD outbreaks ...
Immediate referral to colposcopy versus cytological surveillance for low-grade cervical cytological abnormalities in the absence of HPV test: A systematic review and a meta-analysis of the literature.
Paraskevaidis, Evangelos; M. Arbyn Source: Int J Cancer, Volume 140, Issue 1, p.216-223 (2017) Keywords: Atypical Squamous Cells of the Cervix Colposcopy Cytodiagnosis Disease Management Female Humans Population ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
carcinogenicity evaluating two human in vitro assays: hepatoma-derived cells and hTERT-immortalized renal proximal tubule epithelial cells, representing liver and kidney as major target organs. Cellular systems ...
Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.
microvascular cells were sensitive to endogenous redox changes and underwent apoptosis, but not alveolar epithelial A549 cells. Genotoxic potential of titanium dioxide nanoparticles was investigated using the ...
Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions.
triage Uterine Cervical Neoplasms Vaginal Smears Abstract: BACKGROUND: Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intra-epithelial lesions (LSIL) are minor lesions ...
Modulation of early beta-defensin-2 production as a mechanism developed by type I Toxoplasma gondii to evade human intestinal immunity36564
Toxoplasma Toxoplasmosis treatment Type viability Abstract: We investigated the early innate immune responses induced in human intestinal epithelial cells (IEC) by the three defined Toxoplasma gondii genotype ...
The bovine herpesvirus 4 Bo10 gene encodes a nonessential viral envelope protein that regulates viral tropism through both positive and negative effects.
Laurent Source: J Virol, Volume 85, Issue 2, p.1011-24 (2011) Keywords: Animals Cattle Cell Line Epithelial Cells Gene Deletion Herpesvirus 4, Bovine Molecular Weight Proteome Viral Envelope Proteins Viral ...