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Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.
Molecular Multienzyme Complexes Polyribonucleotide Nucleotidyltransferase Protein Binding Protein Conformation Protein Multimerization Pseudomonas aeruginosa Pseudomonas Phages RNA Helicases Viral Proteins ...
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules36549
results show that multimerization of VHH fragments targeting multiple epitopes on a viral trimeric spike protein is a powerful tool for anti-viral therapy to achieve “best-in-class” and broader ...