Search results - 13 results
Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.
lower response to the vaccine such as anti- CD19, anti- CD20 or anti- CD38 therapies, low (naive) CD4 T-cell counts, genetic or therapeutic Bruton tyrosine kinase deficiency, treatment with ...
Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.
example, immunoreceptor tyrosine-based activation motifs (ITAM) of the envelope transmembrane protein (TM) are essential determinants of infection. Although cell fusion directed by the aminoterminal end of ...
Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).
Radioligand Assay Tyrosine Zinc Abstract: Radioligand binding studies revealed that Ang IV binds to insulin-regulated aminopeptidase (IRAP)/' AT (4) receptors' with high affinity. Yet, as these ...
Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.
exposure expression Functional G protein GPCR Increase IS metabolism metabolites ON rats Reduction regulation report response structure System Transmission trend Tyrosine hydroxylase Abstract: It is ...
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2)4395
3-(2-naphthyl)-d-alanine (d-2-Nal) in position 4. Some of these analogues displayed weak antagonist properties. We tried to strengthen these properties by introducing the structurally modified tyrosine residue ...
Insect neuropeptide and peptide hormone receptors: current knowledge and future directions4400
IS journal KNOWLEDGE Laboratories LEVEL levels Molecular ON ORIGIN Peptides physiology precursor Print problems prospects protein Proteins Proteomics Receptor Receptor Protein-Tyrosine Kinases ...
Insulin-related peptides and their conserved signal transduction pathway479
invertebrates, including nematodes, mollusks, and insects. They initiate an evolutionary conserved signal transduction mechanism by binding to a heterotetrameric, membrane-spanning receptor tyrosine kinase. Recent ...
Beta-cell, thyroid, gastric, adrenal and coeliac autoimmunity and HLA-DQ types in type 1 diabetes22
ICA, PCA, AAA and EmA-IgA by indirect immunofluorescence, and for IA2A (tyrosine phosphatase antibodies), GADA (glutamic acid decarboxylase-65 antibodies) and aTPO by radiobinding assays. The prevalence ...
The presence of thyrogastric antibodies in first degree relatives of type 1 diabetic patients is associated with age and proband antibody status
relatives in relation to age, gender, human leukocyte antigen- DQ type, beta-cell antibody (islet cell, glutamic acid decarboxylase-65, and tyrosine phosphatase antibodies), and proband thyrogastric antibody ...
Individual chaperones required for Yop secretion by Yersinia.
Oligodeoxyribonucleotides Phenotype Protein Conformation Protein Tyrosine Phosphatases Recombinant Proteins Restriction Mapping Sequence Homology, Amino Acid Yersinia enterocolitica Abstract: Pathogenic yersiniae secrete ...