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A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells

microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for genotoxicity ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...

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