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A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Transcriptome Workflow Abstract: The assessment of the carcinogenic potential of chemicals with alternative, human-based in vitro systems has become a major goal of toxicogenomics. The central read-out of these ...
Critical aspects in implementing the OECD monograph No. 14 "the application of the principles of GLP to in vitro studies".
the GLP principles. Furthermore, developments in the area of toxicogenomics, toxicoproteomics, toxicometabonomics and various high throughput screening techniques will also enhance the importance of in ...