Search results - 216 results
A Benchmark Dose-based strategy for evaluating the combined effects of genotoxic compounds
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; Roel Anthonissen; George Johnson; Tamara Vanhaecke; Birgit Mertens Source: BelTox Annual Meeting, Brussels, Belgium (2023) Keywords: benchmark dose modelling genotoxic ...
Towards Characterization and genotoxicity assessment of mycotoxin mixtures present in food.
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; George Johnson; Roel Anthonissen; Pierre Becker; Emmanuel Tangni; Julien Masquelier; Tamara Vanhaecke; Birgit Mertens Source: BelTox Annual Meeting, Brussels, Belgium ...
Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.
result in CVD are not fully understood. To comprehensively describe and understand the pathways through which pollutant exposure leads to cardiotoxicity, a systematic mapping review of the available ...
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
(i) assessment of the uptake and potential crossing of the intestinal barrier by NC, (ii) assessment of local effects, including inflammation and genotoxicity, on the gastrointestinal epithelia, and ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Carole Yauk; Stefaan Verhulst; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: Joint 3R Symposium 2023 (2023) Keywords: genotox ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity Integrated approaches to testing and assessment (IATA) Health ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; Birgit Mertens Source: 57th Congress of the European Soci ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: 57th Congress of the European Societies of Toxicolo ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; Birgit Mertens Source: Joint 3R Symposium, Brussels, Belg ...
Mixtures of genotoxicants: does the principle of additivity apply?
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; Roel Anthonissen; George Johnson; Tamara Vanhaecke; Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: additivity benchmark dose modell ...