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Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based assay.
a combination of the recombinant nucleocapsid protein (NP) and receptor-binding domain (RBD) results in highly specific (99 %) IgG antibody detection five months after infection in 96 % of cases. Although most ...
Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.
Molecular Multienzyme Complexes Polyribonucleotide Nucleotidyltransferase Protein Binding Protein Conformation Protein Multimerization Pseudomonas aeruginosa Pseudomonas Phages RNA Helicases Viral Proteins ...
Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.
Glycosylation Leukemia Virus, Bovine Protein Interaction Domains and Motifs Protein Subunits Viral Envelope Proteins Viral Fusion Proteins Virus Attachment Virus Internalization Virus Replication Abstract: ...
Engineering a nanopore with co-chaperonin function.
alpha hemolysin nanopore to function as GroES, a protein that, in complex with GroEL, forms a two-stroke protein-folding nanomachine. The transmembrane co-chaperonin was prepared by recombination of GroES ...
Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice.
immunogenic. Here we have analyzed the vaccine potential of nine polyketide synthase domains using a DNA prime/protein boost strategy. C57BL /6 mice were vaccinated against the following domains: acyl carrier ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...
The eukaryotic linear motif resource ELM: 10 years and counting.
Volume 42, Issue Database issue (2014) Keywords: Amino Acid Motifs Databases, Protein Internet Multiprotein Complexes Protein Interaction Domains and Motifs Abstract: The eukaryotic linear motif (ELM ...
Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.
previously been characterized in the γ-proteobacteria Pseudomonas and Xanthomonas. These proteins are composed of two MMBL (monocot mannose-binding lectin) domains, a module predominantly and abundantly found ...
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
Bert; Grooten, Johan; Fiers, Walter; Saelens, Xavier Source: PLoS One, Volume 8, Issue 3, p.e59081 (2013) Keywords: Adaptive Immunity Adaptor Proteins, Vesicular Transport Animals Female Humans Immunity, ...
The switches.ELM resource: a compendium of conditional regulatory interaction interfaces.
Amino Acid Motifs Amino Acid Sequence Binding Sites Databases, Protein Molecular Sequence Data Protein Binding Protein Interaction Domains and Motifs Protein Interaction Mapping Protein Interaction Maps ...