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Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.

of structurally diverse secondary metabolites with toxic potential has been identified, but occurrence and relative proportion of the different metabolites in complex mixtures depend on strain, ...

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

observed for rebaudioside A in mice, they have been attributed to the metabolites steviol and steviol glucuronide. We aimed to characterize the pharmacokinetic and pharmacodynamic properties of rebaudioside ...

Biological monitoring of exposure to pesticide residues among Belgian florists

compounds and metabolites) in their urines. A total of 42 urine samples (24-h urines) were collected from florists during their professional activities, on the three most important commercial periods. The ...

Pyrrolizidine alkaloids in food… the good, the bad and the ugly!

biosynthesized by a wide variety of plant species (> 6000), the great majority of them belong to the Asteraceae, Fabaceae and Boraginaceae families. PA s are typical plant secondary metabolites against ...

Monitoring of pyrrolizidine alkaloids in beehive products and derivatives on the Belgian market

secondary plant metabolites thought to be found in approximately 3% of the flowering plants worldwide and exhibiting hepatotoxic properties to humans. As a consequence, beehive products are prone to be ...

Risks for animal health related to the presence of zearalenone and its modified forms in feed

Keywords: animal health risk assessment exposure feed metabolites modified forms toxicity Zearalenone Abstract: Abstract Zearalenone (ZEN), a mycotoxin primarily produced by Fusarium fungi, occurs ...

Slurry photocatalytic membrane reactor technology for removal of pharmaceutical compounds from wastewater: Towards cytostatic drug elimination

compounds and their metabolites, as well as their degraded by-products have genotoxic and mutagenic effects. A major challenge of cytostatic removal stands in the fact that most drugs are delivered to ...

Endocrine activity of mycotoxins and mycotoxin mixtures.

endocrine activity of 13 mycotoxins and their mixtures. As expected, zearalenone and its metabolites α-zearalenol and β- zearalenol turned out to have the strongest estrogenic potency (EC50 8,7 10-10 ± 0,8; ...

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