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Determination of vaccine bacterial endotoxins content by the rFC method [1]

Effectiveness and safety of vaccines, medicines and health products - Quality of medical laboratories   [2]

Scientific poster, presentation or proceeding

English

SCIENSANO

Authors

Flore Laurent [3]

Keywords

  1. Endotoxin; vaccine; quality control; recombinant factor c; LAL [4]

Abstract:

Sciensano, as official medicines control laboratory (OMCL) following “Official Control Authority Batch Release” (OCABR) guidelines, is entitled to check the concentration of endotoxin in bacterial vaccines. The limulus amebocyte lysate (LAL) and the recombinant factor C (rFC) assays are suitable for all vaccines tested. The rFC method has been implemented at Sciensano for batch release of vaccines since March 2023.
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Associated health topics:

Effectiveness and safety of vaccines, medicines and health products - Quality of medical laboratories [2]
Source URL:https://www.sciensano.be/en/biblio/determination-vaccine-bacterial-endotoxins-content-rfc-method

Links
[1] https://www.sciensano.be/en/biblio/determination-vaccine-bacterial-endotoxins-content-rfc-method [2] https://www.sciensano.be/en/health-topics/effectiveness-and-safety-vaccines-medicines-and-health-products-quality-medical-laboratories [3] https://www.sciensano.be/en/people/flore-laurent/biblio [4] https://www.sciensano.be/en/biblio?f%5Bkeyword%5D=38236&f%5Bsearch%5D=Endotoxin%3B%20vaccine%3B%20quality%20control%3B%20recombinant%20factor%20c%3B%20LAL