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Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Lefebvre, David; Lanke, Kjerstin H W; Kris De Clercq; Hilgenfeld, Rolf; Neyts, Johan; van Kuppeveld, Frank J M Source: Antiviral Res, Volume 103, p.17-24 (2014) Keywords: 3C Viral Proteases Animals Antiviral ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

Substitution Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Enzyme Inhibitors Genetic Variation Imidazoles Pyridines RNA Replicase Swine Viral Proteins Abstract: Classical swine fever ...

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules36549

Antibodies,Neutralizing Antibody Antibody Specificity Antiviral Agents article Binding Sites Biology biosynthesis Camelids,New World Cross Reactions Dose-Response Relationship,Immunologic electronic Epitopes genetics ...

Development of a foot-and-mouth disease infection model in severe combined immunodeficient mice for the preliminary evaluation of antiviral drugs.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Neyts, J; Kris De Clercq Source: Transbound Emerg Dis, Volume 57, Issue 6, p.430-3 (2010) Keywords: Animals Antiviral ...

The reduction of CSFV transmission to untreated pigs by the pestivirus inhibitor BPIP: a proof of concept.

Microbiol, Volume 139, Issue 3-4, p.365-8 (2009) Keywords: Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Imidazoles Palatine Tonsil Pyridines Sus scrofa Viral Load Viremia Virus ...

Modulating mouse innate immunity to RNA viruses by expressing the Bos taurus Mx system.

interferon-induced members of the dynamin superfamily of large guanosine triphosphatases. These proteins have attracted much attention because some display antiviral activity against pathogenic RNA viruses, such as ...

Community transmission of influenza A (H1N1)v virus at a rock festival in Belgium, 2-5 July 200936827

Euro.Surveill, Volume 14, Issue 31 (2009) Keywords: 0 2009 a additional Adult Agent Agents Anniversaries and Special Events antibiotic prophylaxis Antiviral Agents Area Areas article at Belgian Belgium Case ...

Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.

Marie-Frédérique; Neyts, Johan; F. Koenen Source: J Gen Virol, Volume 90, Issue Pt 6, p.1335-42 (2009) Keywords: Administration, Oral Animals Antiviral Agents Classical Swine Fever Classical swine fever virus ...

A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.

Substitution Animals Antiviral Agents Benzodioxoles Cattle Cell Line Diarrhea Virus 1, Bovine Viral Diarrhea Virus 2, Bovine Viral Drug Resistance, Viral Hepacivirus Inhibitory Concentration 50 Models, Molecular ...

Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season36834

Source: Emerg.Infect.Dis., Volume 15, Issue 4, Number 560, p.552- 560 (2009) Keywords: 0 2007 2008 a Activity acute Agent Agents antagonists & inhibitors Antiviral Agents article classification Clinical ...

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