Search results - 7 results

Modeling the migration of chemicals from food contact materials to food: The MERLIN-expo/VERMEER toolbox

simulations showed a good match between predicted and experimental values. The tested models can be used to provide insights in the amount and the type of toxicological data that are needed for the safety ...

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

Next, the dietary exposure of the Belgian population to mineral oil was assessed by combining the analytical results with consumption data of the Belgian Food Consumption Survey. Overall, the exposure to ...

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

safety. By combining in silico predictions with existing in vitro and in vivo genotoxicity data from publicly available literature sources and results from in vitro gene mutation experiments, the 106 study ...

Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay

a dry food migration experiment. By measuring an overall estrogenic activity, known and unknown estrogenic chemicals and mixture effects are taken into account and the data are compared to molecule ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

5 known positive and 5 known negative test compounds for genotoxicity was evaluated. In addition, 2 compounds with debatable genotoxicity data were tested to explore how the qPCR array would classify these. ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

two structure-activity relationship (SAR) software programs. For substances yielding structural alerts in both models, genotoxicity data were collected from previous European evaluations in a non- FCM ...

Study of the possible migration risks of food contact materials for children under 3 years

etc.) that could not be identified before were elucidated here. Additionally, the same extracts were analysed also by LC- QTOF- MS under MSE mode. The full-spectrum accurate mass data of both ...

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