Search results - 22 results

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

December 2019. COVID-19 cases are confirmed by the detection of SARS-CoV-2 RNA in biological samples by RT-qPCR. However, limited numbers of SARS-CoV-2 genomes were available when the first RT-qPCR methods ...

Comparison of SNP-based subtyping workflows for bacterial isolates using WGS data, applied to Salmonella enterica serotype Typhimurium and serotype 1,4,[5],12:i:.

PLoS One, Volume 13, Issue 2 (2018) Keywords: bacterial phylogeny; food-borne; genes; NGS; WGS; computational biology/bioinformatics; disease outbreaks; outbreak; performance evaluation; pipeline; ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

basis of comparative interactomics of multiple strains is an effective strategy to highlight correlations between host proteome hijacking and biological or pathogenic traits. Here, we developed an ...

Attenuation of RNA viruses by redirecting their evolution in sequence space.

Poirier, Enzo Z; Vallet, Thomas; Boussier, Jeremy; Mounce, Bryan C; Fontes, Magnus; Vignuzzi, Marco Source: Nat Microbiol, Volume 2, p.17088 (2017) Keywords: Adaptation, Biological Animals Antibodies, ...

Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.

Interaction of viral envelope proteins with host cell membranes has been extensively investigated in a number of systems. However, the biological relevance of these interactions in vivo has been hampered by the ...

Melanoma burden by melanoma stage: Assessment through a disease transition model

Male Markov Chains Melanoma Models, Biological Neoplasm Recurrence, Local Neoplasm Staging Quality of Life Skin Neoplasms Tumor Burden Abstract: BACKGROUND: The total burden of melanoma has already been ...

Changes in Meningococcal Strains in the Era of a Serogroup C Vaccination Campaign: Trends and Evolution in Belgium during the Period 1997-2012.

(2015) Keywords: ADOLESCENT Adult Belgium Biological Evolution Child Child, Preschool DNA, Bacterial Female Humans Infant Male Meningococcal Infections Meningococcal Vaccines Multilocus Sequence Typing ...

Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage20

p.242- 249 (2015) Keywords: Africa Allergy analysi analysis application applications article Asia association Australia Belgium Biological Evolution Biology Biotechnology Brussels care Cell CHILDREN ...

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