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Efficacy of chimeric Pestivirus vaccine candidates against classical swine fever: protection and DIVA characteristics.
protect pigs against clinical signs, and to reduce virus shedding and virus transmission, after a challenge with CSF virus (CSFV), 7 or 14 days after a single intramuscular vaccination. In these vaccine ...
CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.
C-strain vaccines were compared for their efficacy to induce protection against a CSF virus (CSFV) challenge with the moderately virulent Bas-Rhin isolate, in pigs as early as two days post-immunization. ...
Efficacy of rHVT-AI vector vaccine in broilers with passive immunity against challenge with two antigenically divergent Egyptian clade 2.2.1 HPAI H5N1 strains.
10 days. The different groups were challenged with two antigenically highly divergent Egyptian dade 2.2.1 H5N1 HPAIV s at 4 wk of age. Protection against challenge was compared with unvaccinated birds ...
Potency of a recombinant NDV-H5 vaccine against various HPAI H5N1 virus challenges in SPF chickens.
viruses. Obtained protections were dependent on the age of the chickens, on the constructs and, in particular, on the homology between the HA that was inserted and the challenge strains. The objective of ...
Immune responses and protection against H5N1 highly pathogenic avian influenza virus induced by the Newcastle disease virus H5 vaccine in ducks.
IgY response were higher in ducks with NDV MDA. To our knowledge, this is the first report of the use of an NDV vector in ducks and of an HPAI H5N1 challenge in mule ducks, which appeared to be as ...
Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge.
starting from 3 to 7 days postchallenge (1.0 to 5.0 log2). In contrast, the unvaccinated gilts remained negative for VN antibodies after challenge. The vaccinated gilts had shorter viremia than the control ...
Efficacy of marker vaccine candidate CP7_E2alf in piglets with maternally derived C-strain antibodies.
their mock-vaccinated littermate controls were challenged 2 weeks post vaccination with highly virulent Classical swine fever virus (CSFV) strain “Koslov”. CP7_E2alf provided clinical protection upon ...
Characteristics of serology-based vaccine potency models for foot-and-mouth disease virus.
of animals each year. Despite considerable efforts during the past decades, a challenge-free alternative vaccine potency test to replace the European protective dose 50% test (PD (50)) has not been ...
Comparative evaluation of live marker vaccine candidates "CP7_E2alf" and "flc11" along with C-strain "Riems" after oral vaccination.
candidates the chimeric pestiviruses “ CP7_E2alf” and “flc11” were identified. Within an international research project, these candidates were comparatively tested in challenge experiments after a single oral ...
Towards licensing of CP7_E2alf as marker vaccine against classical swine fever-Duration of immunity.
later, all animals were oronasally challenged with highly virulent CSF virus (CSFV) strain “Koslov”. Upon vaccination, all but one orally and all intramuscularly vaccinated pigs developed rising and later ...