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Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

human PPAR y2. 2) DRE- CALUX (dioxin responsive element) uses a third H1L7.5c1 generation cell line, derived from the mouse hepatoma hepa1c1c7 wild‐type cells, which contain the AhR receptor and 3) The ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

resistance mutations, (b) do not distinguish living from dead cells, (c) ignore all intrinsic resistance mechanisms, and (d) ignore the influence of compensatory mutations. Objectives We introduce ...

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