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A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...

Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.

Ghislaine Source: Toxicol In Vitro, Volume 33, Number 135, p.125-35 (2016) Keywords: Apoptosis Capillaries Cell Cycle Checkpoints Cell Line Cell Line, Tumor Cell Survival DNA Damage Glutathione Heat-Shock ...

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