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NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health.

Colussi, Loek; Pruppers, Mathieu; Baaken, Dan; Bogdanova, Anna Source: Int J Environ Res Public Health, Volume 20, Issue 12 (2023) Keywords: Cell Phone Electromagnetic Fields environmental exposure Humans ...

Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.

damage induced by known mutagens) were investigated in the human B lymphoblastoid (TK6) cell line. Cells were exposed to 50 Hz  MF at three selected magnetic flux densities (i.e., 10, 100, and 500 μT) for ...

Impact of experimental design factors on the potency of genotoxicants in in vitro test

that of more traditional statistical methods based on lowest observed genotoxic effect levels. When comparing the in vitro  MN results obtained in both cell lines with the BMD covariate approach, ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

composed of small or large agglomerates with similar dispersion medium composition. For in vitro testing, human bronchial epithelial (HBE), colon epithelial (Caco2) and monocytic (THP-1) cell lines were ...

Is aggregated synthetic amorphous silica toxicologically relevant?

stronger effects in all the cell lines than the aggregated suspension (AGGR). We then compared DE- AGGR with 2 suspensions fractionated from AGGR: the precipitated fraction (PREC) and the supernatant ...

NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program

in Belgium. DNA samples derived from cell line mixes and artificially mutated cell lines, designed to carry variants of clinical relevance occurring in solid tumors, hematological malignancies, and ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

In this manuscript, an optimized protocol for a combined in vitro comet/micronucleus study to investigate these effects in a human lymphoblastoid cell line (TK6) is provided including the description ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

human PPAR y2. 2) DRE- CALUX (dioxin responsive element) uses a third H1L7.5c1 generation cell line, derived from the mouse hepatoma hepa1c1c7 wild‐type cells, which contain the AhR receptor and 3) The ...

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