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The possibilities of chemometrics in API and counterfeit testing

Publication Type: Scientific poster, presentation or proceeding Authors: Eric Deconinck Source: Counterfeit Symposium EDQM, NA, Issue EDQM, NA (2017) Keywords: Chemometrics Counterfeit Health ...

Clustering and diagnostic modelling of slimming aids based on chromatographic and mass spectrometric fingerprints

highly informative fingerprints. Three types of fingerprints were acquired (PDA, Total Ion Chromatograms (TIC), and MS fingerprints) which were used in the chemometric data analysis. Both unsupervised ...

API WG project: Chemometric results for Atorvastatin

Publication Type: Scientific poster, presentation or proceeding Authors: Eric Deconinck; Acevska,J. Source: Counterfeit Working Group, NA, Issue EDQM, NA (2016) Keywords: Counterfeit result results working group Health Topics:  Effectiveness and safety of ...

Chemometrics and the identification of counterfeit medicines-A review.

of actual case studies dealing with verifying the authenticity of selected medicines supported by different chemometric approaches. In particular, a general data processing workflow is discussed with ...

Detection and risk evaluation of counterfeit medicines based on physico-chemical properties: the fingerprint and chemometrics approach

Publication Type: Dissertation Authors: Custers, Deborah Source: UAntwerpen, Antwerp, Belgium, p.291 (2016) Accession Number: NA Keywords: Chemometrics Counterfeit medicines detection fingerprint ...

Discriminating nicotine and non-nicotine containing e-liquids using infrared spectroscopy.

chemometrics was evaluated for the discrimination between nicotine containing and non-nicotine containing samples. It could be concluded that both ATR- IR and NIR could be used for the discrimination when ...

Testing of complementarity of PDA and MS detectors using chromatographic fingerprinting of genuine and counterfeit samples containing sildenafil citrate.

for the analysis of genuine Viagra®, generic products of Viagra®, and counterfeit samples in order to obtain different types of fingerprints. These data were included in the chemometric data analysis, ...

ATR-FTIR spectroscopy and chemometrics: An interesting tool to discriminate and characterize counterfeit medicines.

evaluation of suspected samples. This study proposes a combination of ATR- FTIR and chemometrics to discriminate and classify counterfeit medicines. A sample set, containing 209 samples in total, was analyzed ...

Detection of sibutramine in adulterated dietary supplements using attenuated total reflectance-infrared spectroscopy.

adulterated dietary supplements. Data interpretation was performed using different basic chemometric techniques. It was found that the use of ATR- IR combined with the k-Nearest Neighbours (k- NN) was able to ...

Detection of whitening agents in illegal cosmetics using attenuated total reflectance-infrared spectroscopy.

attenuated total reflectance-infrared (ATR- IR) spectroscopy, combined with chemometrics, was evaluated for that purpose. It was found that the combination of ATR- IR with the simple chemometric technique ...

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