Search results - 144 results

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

a cluster of genes that encodes components of the FAS- II (fatty acid synthase II) complex, which is targeted by isoniazid. On the other hand, a remarkable down-regulation of the NADH-dehydrogenase (ndh) ...

Positive epistasis of major low-cost drug resistance mutations rpoB531-TTG and katG315-ACC depends on the phylogenetic background of Mycobacterium tuberculosis strains.

clustering was higher in modern versus ancient Beijing strains (35.9% vs. 12.1%; P  <0.001). After taking into consideration the presence of rpoB and katG mutations, clustering decreased to 15.9% in modern ...

Model-Based Classification for Digital PCR: Your Umbrella for Rain.

reduces accuracy, the uncertainty of this classification is typically ignored. We introduce a model-based clustering method to estimate the probability that the target is present (absent) in a partition ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

down-regulated genes. As an example and in accordance with previous studies, the highest induced genes in the presence of isoniazid belong to a cluster of genes that encodes components of the FAS- II (fatty acid ...

Clustering and diagnostic modelling of slimming aids based on chromatographic and mass spectrometric fingerprints

(2017) Keywords: Anti-Obesity Agents Chromatography, High Pressure Liquid Cluster Analysis Discriminant Analysis Least-Squares Analysis Mass Spectrometry Principal Component Analysis Abstract: Herbal ...

Toward a Novel Multilocus Phylogenetic Taxonomy for the Dermatophytes.

Freeke, Joanna; Göker, Markus; Rezaei-Matehkolaei, Ali; Mirhendi, Hossein; Gräser, Yvonne Source: Mycopathologia, Volume 182, Issue 1-2, p.5-31 (2017) Keywords: Animals Cluster Analysis DNA, Fungal DNA, ...

Lactarius subgenus Russularia (Basidiomycota, Russulales): novel Asian species, worldwide phylogeny and evolutionary relationships.

Dirk Stubbe; Hyde, Kevin D; Verbeken, Annemieke; Nuytinck, Jorinde Source: Fungal Biol, Volume 120, Issue 12, Number 1581, p.1554-1581 (2016) Keywords: Asia Basidiomycota Cluster Analysis Coniferophyta ...

Evolutionary History and Ongoing Transmission of Phylogenetic Sublineages of Mycobacterium tuberculosis Beijing Genotype in China.

The higher clustering of the modern isolates in children and lack of increased MDR rate in any sublineage suggest that not association with drug resistance but other (e.g., speculatively, ...

Chemometrics and the identification of counterfeit medicines-A review.

Techniques, Analytical Cluster Analysis Counterfeit Drugs Discriminant Analysis Drug Contamination Models, Theoretical Pattern Recognition, Automated Abstract: This review article provides readers with a number ...

Predominance of influenza A(H1N1)pdm09 virus genetic subclade 6B.1 and influenza B/Victoria lineage viruses at the start of the 2015/16 influenza season in Europe

the European influenza 2015/16 season. Most analysed viruses clustered in a new genetic subclade 6B.1, antigenically similar to the northern hemisphere vaccine component A/California/7/2009. The ...

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