Search results - 9 results
Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
Batch release testing for human and veterinary tetanus vaccines still relies heavily on methods that involve animals, particularly for potency testing. The quantity and quality of tetanus antigen present ...
Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
having been specifically developed as alternatives to in vivo potency tests. These methods require at least one well characterised monoclonal antibody (mAb) that is specific for the target antigen. In this ...
Regulatory issues regarding manufacture and control of vaccine adjuvants. The EU situation.
components that potentiate the immune responses to an antigen and/or modulate it towards the desired immune responses. Adjuvants can be classified according to their source, mechanism of action, or physical or ...
Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.
Issue 5, Number 3047, p.3041-7 (2001) Keywords: Acyltransferases Animals Antibodies, Bacterial Antigens, Bacterial Bacterial Proteins BCG Vaccine CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes ...
Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.
p.3854-60 (2000) Keywords: Acyltransferases Animals Antibodies, Bacterial Antigens, Bacterial BCG Vaccine Biolistics Female Humans Injections, Intramuscular Interferon-gamma Interleukin-10 Interleukin-2 ...
Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.
p.1040-7 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine Cloning, Molecular Cytokines mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Weight Vaccines, DNA Abstract: Using spleen cells from ...
Immunogenicity and protective efficacy of DNA vaccines encoding secreted and non-secreted forms of Mycobacterium tuberculosis Ag85A.
Dis, Volume 79, Issue 4, Number 259, p.251-9 (1999) Keywords: Acyltransferases Animals Antigens, Bacterial BCG Vaccine Female mice Mice, Inbred BALB C Mycobacterium tuberculosis Tuberculosis Vaccines, ...
Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex.
M A Source: Vaccine, Volume 15, Issue 8, Number 833, p.830-3 (1997) Keywords: Animals Antibodies, Bacterial Antigens, Bacterial BCG Vaccine Cell Division Cytokines DNA, Bacterial Injections, Intramuscular mice ...
Differences in Antigenic Structure of Inactivated Polio Vaccines Made From Sabin Live-Attenuated and Wild-Type Poliovirus Strains: Impact on Vaccine Potency Assays.
Alexandre Dobly Source: J Infect Dis, Volume 221, Issue 4 (2020) Keywords: Antibodies, Neutralizing Antibodies, Viral Antigens, Viral Humans Immunogenicity, Vaccine Poliomyelitis Poliovirus Poliovirus ...