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Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.
Publication Type: Peer reviewed scientific article Authors: D'Souza, Sushila; Marta Romano; Korf, Johanna; Wang, Xiao-Ming; Adnet, Pierre-Yves; Huygen, Kris Source: Infect Immun, Volume 74, ...
Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.
Publication Type: Peer reviewed scientific article Authors: Marta Romano; D'Souza, Sushila; Adnet, Pierre-Yves; Laali, Rachid; Fabienne Jurion; Palfliet, Kamiel; Huygen, Kris Source: Vaccine, ...
Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.
Publication Type: Peer reviewed scientific article Authors: Marta Romano; Olivier J Denis; D'Souza, Sushila; Wang, Xiao-Ming; Ottenhoff, Tom H M; Brulet, Jean-Marc; Huygen, Kris Source: ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
Publication Type: Peer reviewed scientific article Authors: Denis, Olivier; Stroobant, Vincent; Colau, Didier; D'Souza, Sushila; Huygen, Kris Source: Immunol Lett, Volume 81, Issue 2, p.115-24 ...
CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.
Publication Type: Peer reviewed scientific article Authors: D'Souza, S; Denis, O; Scorza, T; Nzabintwali, F; Verschueren, H; Huygen, K Source: Eur J Immunol, Volume 30, Issue 9, Number 2459, ...
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine.
https://www.sciensano.be/en/biblio/immunogenicity-and-protective-efficacy-a-tuberculosis-dna-vaccine
Publication Type: Peer reviewed scientific article Authors: Huygen, K; Content, J; Denis, O; Montgomery, D L; Yawman, A M; Deck, R R; C M DeWitt; Orme, I M; Baldwin, S; D'Souza, C; Drowart, A; ...