Search results - 8 results
The reduction of CSFV transmission to untreated pigs by the pestivirus inhibitor BPIP: a proof of concept.
Replication Abstract: 5-[(4-Bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine (BPIP) is a representative molecule of a novel class of highly active in vitro inhibitors of the replication of Classical ...
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
Imidazoles Leukopenia Palatine Tonsil Pyridines Swine Viral Load Viremia Abstract: 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine (BPIP) is a representative of a class of imidazopyridines with ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
Three-Dimensional Imidazoles Inhibitory Concentration 50 Models, Molecular Molecular Structure polymerase chain reaction Pyridines RNA Replicase RNA, Viral Sequence Analysis, DNA Structure-Activity Relationship Virus ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine [BPIP]and VP32947) is also resistant to AG110. AG110 did not inhibit the in vitro activity of recombinant BVDV RdRp but inhibited the activity of BVDV replication complexes (RC s). ...
Contaminants in organically and conventionally produced winter wheat (Triticum aestivum) in Belgium.
to be taken into account (0.11 microg chlorpyriphos-methyl, 0.2 microg dichlorvos and 0.24 microg pirimiphos-methyl kg(-1) bw). When expressed as a percentage of the tolerable/acceptable daily intake ...
Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code.
associated with DNA methylation and decreased accessibility of promoter sequences. HDAC1 and the transcriptional corepressor mSin3A are associated with the inactive but not the reactivated promoter. Silencing ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Replicase RNA, Viral Triazines Tumor Cells, Cultured Virus Replication Abstract: We report on the highly potent and selective antipestivirus activity of 5-[(4-bromophenyl)methyl ...
Immunity and effect of clopidol/methyl benzoquate and robenidine before and after weaning on rabbit coccidiosis in the field.
months the anticoccidial effect of 200 ppm clopidol/methyl benzoquate and of 50 ppm robenidine, and the development of immunity against five different species of Eimeria were followed in a closed rabbit ...