Search results - 36 results
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
Imidazoles Leukopenia Palatine Tonsil Pyridines Swine Viral Load Viremia Abstract: 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine (BPIP) is a representative of a class of imidazopyridines with ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
Three-Dimensional Imidazoles Inhibitory Concentration 50 Models, Molecular Molecular Structure polymerase chain reaction Pyridines RNA Replicase RNA, Viral Sequence Analysis, DNA Structure-Activity Relationship Virus ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo [4,5-c]pyridine [BPIP]and VP32947) is also resistant to AG110. AG110 did not inhibit the in vitro activity of recombinant BVDV RdRp but inhibited the activity of BVDV replication complexes (RC s). ...
Contaminants in organically and conventionally produced winter wheat (Triticum aestivum) in Belgium.
to be taken into account (0.11 microg chlorpyriphos-methyl, 0.2 microg dichlorvos and 0.24 microg pirimiphos-methyl kg(-1) bw). When expressed as a percentage of the tolerable/acceptable daily intake ...
Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code.
associated with DNA methylation and decreased accessibility of promoter sequences. HDAC1 and the transcriptional corepressor mSin3A are associated with the inactive but not the reactivated promoter. Silencing ...
Resistance to vanadium in Pseudomonas fluorescens ATCC 17400 caused by mutations in TCA cycle enzymes36759
second mutant had the transposon inserted into acnD, one out of three genes coding for a 2-methyl-isocitrate dehydratase (aconitase). In this mutant, there was a higher level of acnB aconitase transcripts ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Replicase RNA, Viral Triazines Tumor Cells, Cultured Virus Replication Abstract: We report on the highly potent and selective antipestivirus activity of 5-[(4-bromophenyl)methyl ...
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor4407
agonist of the stable fly (Stomoxys calcitrans) tachykinin receptor, STKR. By means of synthetic analogues, the Gly/Ala exchange, representing the addition of a single methyl group in the active core region ...
Validation of HPLC Analysis of 2-Phenoxyethanol, 1-Phenoxypropan-2-ol, Methyl, Ethyl, Propyl, Butyl and Benzyl 4-Hydroxybenzoate (Parabens) in Cosmetic Products, with Emphasis on Decision Limit and Detection Capability
Publication Type: Peer reviewed scientific article Authors: Borremans,M.; Joris Van Loco; Roos,P.; Goeyens,L. Source: Chromatographia, Volume 59, Issue 1-2, Number 53, p.47- 53 (2004) Keywords: Absence ALL analysis Calibration data Decision detection Dete ...
Half-fraction and full factorial designs versus central composite design for retention modelling in reversed-phase ion-pair liquid chromatography
(LC) retention modelling of the cough-syrup compounds methyl para-hydroxybenzoate (MPHB) and propyl para-hydroxybenzoate (PPHB), phenylephrine hydrochloride (PE) and chlorphenamine maleate (CPM) was ...