Search results - 384 results
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors31058
Design DRUG Drug Design drug effects Drug Synergism electronic Ethionamide EVALUATION exposure expression France Human im IS journal Macrophages metabolism mice microbiology Microsomes,Liver ...
A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation86
Source: J.Clin.Pharmacol. (2011) Keywords: 0 a accuracy acid acute Adult Agent Agents Analyses approach approaches article AS at Combination corticosteroids Covariate Demographic Design DRUG drugs ...
Influenza A/H1N1 vaccine in patients treated by kidney transplant or dialysis: a cohort study36521
Class clinic Cohort Studies Cohort study Combination Confidence Intervals Control data Design disease DRUG Drug Combinations electronic Female GM Histocompatibility Antigens Class I Histocompatibility ...
Does country influence the health burden of informal care? An international comparison between Belgium and Great Britain36539
Logistic-regression Long-term Male methodology middle aged ON Paper Patient patients POLICIES POLICY regression Research Research Design Research Support residence result results SB- IM Self Report Social Environment ...
Is individual educational level related to end-of-life care use? Results from a nationwide retrospective cohort study in Belgium.
explaining differential end-of-life care use. RESEARCH DESIGN: A retrospective cohort study via a nationwide sentinel network of general practitioners (GP s; SENTI- MELC Study) provided data on end-of-life ...
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.
NCX1. RESEARCH DESIGN AND METHODS: Biologic and morphologic methods (Ca(2+) imaging, Ca(2+) uptake, glucose metabolism, insulin release, and point counting morphometry) were used to assess β-cell function ...
Biosafety in laboratory animal facilities. A practical approach.
approaches AS aspects Belgium biosafety care Contained use containment criteria Design Directive 2009/41/EC environment European external genetically Genetically modified Genetically modified organism ...
Mortality associated with in-hospital bacteraemia caused by Staphylococcus aureus: a multistate analysis with follow-up beyond hospital discharge.
1 July 2005 and 30 June 2006. All patients (n = 3132) in the same wards as the patients infected with S. aureus were included. We addressed key weaknesses in previous studies by using a cohort design and ...
The consistency approach for quality control of vaccines- a strategy to improve quality control and implement 3Rs
Control recommendation Recommendations report Research Design routine SB- IM STANDARD standards Strategies Strategy System Test TESTING tests The Netherlands use vaccine vaccines veterinary Veterinary ...
Human biomonitoring on heavy metals in Ath: methodological aspects.
paper describes the study design and methodology used to carry out this human biomonitoring.A random sampling was done in the general population, in two areas of Ath: an area centered around the ...