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Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.
Pieter Source: Biologicals, Volume 74 (2021) Abstract: There is an increasing need to establish quality principles for designing, developing and manufacturing challenge agents as currently these agents are ...
Whole-Genome Sequencing-Based Antimicrobial Resistance Characterization and Phylogenomic Investigation of 19 Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Positive Escherichia coli Strains Collected From Hospital Patients in Benin in 2019.
constitutes a serious threat to global public health. Surgical site infections are associated with high morbidity and mortality rates in developing countries, fueled by the limited availability of effective ...
Population vulnerability to COVID-19 in Europe: a burden of disease analysis
countries in Europe. YLD was restricted to a list of specific health conditions associated with being at risk of developing severe consequences from COVID-19 based on guidance from the United Kingdom ...
Reflections on key methodological decisions in national burden of disease assessments
methodological decisions and challenges drawing on the experiences of countries working with BoD methodology in their own national studies. Each of these steps are briefly described and, where appropriate, some ...
All in one method for the analysis of multiclass food additives using UHPLC-MS/MS
global trade with countries subjected to different regulations, focusing only on authorized food additives may not be enough to guarantee food safety. To protect the consumers, national authorities have to ...
Comparative dissolution study on substandard and falsified antibiotics encountered in Belgium
developing and developed countries, posing a growing threat to public health. It has been demonstrated that SF products of these essential life-saving medicines could cause treatment failures, antimicrobial ...
Accuracy of combinations of visual inspection using acetic acid or lugol iodine to detect cervical precancer: a meta-analysis.
with acetic acid (VIA) or with Lugol’s iodine (VILI) have been evaluated for cervical cancer screening in developing countries. OBJECTIVES: To assess the diagnostic accuracy and clinical utility of ...
Epidemiology, Impact and Control of Rabies in Nepal: A Systematic Review
encephalitis if effective post-exposure prophylaxis is not provided. Rabies occurs worldwide, but its burden is disproportionately high in developing countries, including Nepal. We aimed to summarize current ...
Cryptococcus neoformans population diversity and clinical outcomes of HIV-associated cryptococcal meningitis patients in Zimbabwe.
meningitis co-infection is a major public health problem in most developing countries. Cryptococcus neoformans sensu stricto is responsible for the majority of HIV-associated cryptococcosis cases in ...
Detection and risk evaluation of counterfeit medicines based on physico-chemical properties: the fingerprint and chemometrics approach
physico-chemical properties risk evaluation Abstract: Counterfeit medicines pose a global threat to public health; both developing and industrialized countries are exposed to pharmaceutical forgery. These products ...