Search results - 248 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

Rodwell,; Mathys, Vanessa Source: Lancet Microbe, Volume 3, Issue 4 (2022) Keywords: Drug Resistance mutations Tuberculosis Abstract: Background: Molecular diagnostics are considered the most promising route ...

Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.

CONCLUSIONS: Our study confirms the effectiveness of WGS for the rapid detection of complex and its drug resistance profiles for first-line drugs even when working directly on MGIT tubes, and supports the ...

Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.

Source: Eur Respir J (2020) Abstract: Conventional molecular tests for detecting complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole genome sequencing (WGS) typically ...

Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study.

learned to be considered for the future development of a WGS-based surveillance system. WGS and epidemiological data of patients with rifampicin (RR) and multi-drug resistant (MDR)-tuberculosis (TB) were ...

The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).

Democratic Republic of the Congo Drug Resistance Female Humans Malaria, Falciparum Male middle aged Mutation Plasmodium falciparum Polymorphism, Genetic Young adult Abstract: Artemisinin-based combination ...

Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance.

Child Child, Preschool Chloroquine Democratic Republic of the Congo Dried Blood Spot Testing Drug Resistance Humans Infant Infant, Newborn Malaria, Falciparum Mass Screening Membrane Transport Proteins ...

Superficial mycoses in Belgium: Burden, costs and antifungal drugs consumption

Issue 5, Number 508 (2020) Keywords: antifungal drugs consumption Belgium burden of disease Candidiasis Cost dermatophytosis Disability-Adjusted Life Years superficial mycosis Abstract: Background ...

Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza

how NGS could be implemented to detect drug resistance mutations in clinical influenza virus isolates. Health Topics:  Flu Griep Grippe Manuscript versions:  DOI:  ...

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