Search results - 8 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

Walker; CRyPTIC Consortium; Seq&Treat Consortium; Derrick W Crook; Nazir Ismail; Timothy C Rodwell; Vanessa Mathys Source: Lancet Microbe, Volume 3, Issue 4 (2022) Keywords: Drug Resistance mutations ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Pieter-Jan Ceyssens Source: 39th Annual Congress of the European Society of Mycobacteriology, Issue ESM, Dresden, Germany (2018) Keywords: drug susceptibility testing Mycobacterium tuberculosis Health Topics:  ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...

Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.

Maryse; Saegerman, Claude; Vanessa Mathys Source: PLoS One, Volume 12, Issue 2, p.e0172554 (2017) Keywords: ADOLESCENT Adult Bacterial Typing Techniques Belgium Child Cluster Analysis Contact Tracing Drug ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria. 34 clinical M. tuberculosis isolates were investigated for their resistance profile to four different drugs (rifampicin, isoniazid, ethambutol and linezolid), yielding a 100% concordance to the ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria, 88.03%. Five organisms were misidentified. A novel method of drug resistance testing was also presented, which uses semi-quantitative measurement of bacterial biomass by creating MALDI- TOF spectra ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains to ...

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